Root coverage achieved with a connective tissue graft overlaid onto allogeneic demineralized dentin matrix incorporated with rhBMP-2
곽한울, 엄인웅, 구정귀,
소속 상세정보
곽한울 ( Kwak Han-Wool ) -
엄인웅 ( Um In-Woong ) -
구정귀 ( Ku Jeong-Kui ) -
Abstract
Autogenous demineralized dentin matrix (DDM) has been widely used in implant dentistry and highlighted as a potential carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2). Allogeneic DDM (Allo-DDM) is comparable to autogenous DDM in safety and effectiveness. The various endogenous growth factors in dentin, including BMP, transforming growth factor, fibroblast growth factor, and insulin growth factor suggest that DDM incorporated with rhBMP-2 (DDM/ rhBMP-2) may exert a synergistic effect that promotes soft tissue healing through angiogenic activity, in addition to its osteoinductivity. This case report describes a successful outcome of root coverage where connective tissue graft (CTG) was overlaid onto Allo-DDM incorporated with rhBMP-2 (Allo-DDM/rhBMP-2).
키워드
demineralized dentin matrix; connective tissue graft; fistula closure; dentistry; root coverage
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